A cleanroom is a controlled environment used for highly sensitive manufacturing and production operations. The level of cleanliness in a cleanroom is defined by the allowable concentration of airborne particles, with other environmental parameters (e.g. temperature, air pressure, and humidity) controlled as necessary for any given process. Achieving and maintaining the level of cleanliness needed for these sensitive applications necessitates the use of innovative particulate filtration technology (HEPA and ULPA). In addition to airborne particles, airborne molecular contamination is an increasingly important driver of process performance, requiring molecular or gas phase filtration media.

For advanced materials, you can trust in your most critical filtration applications, turn to the experts at Hollingsworth & Vose (H&V). We manufacture highly engineered HEPA and ULPA particulate filter media as well as molecular filter media (MFM). H&V’s materials help control contamination, ensuring process integrity and optimizing process yields. H&V’s differentiated solutions reducing the energy consumption of cleanroom filtration systems, a significant portion of overall cleanroom costs. All of our filtration products are designed and constructed to meet the most stringent requirements of all relevant international standards.

The Role of Filtration Systems in Cleanrooms

The filtration system is the critical component in any cleanroom, as it keeps the cleanroom free of contaminants that threaten the quality, safety, and yield of the process being protected. A cleanroom filtration system uses multiple filters to remove and collect particles from incoming air. The flow of air in a cleanroom is carefully engineered to facilitate the control of airborne contamination by ensuring air moves in a single direction (laminar or unidirectional). This airflow design minimizes the risk of contaminants traveling through and landing inside of the cleanroom rather than getting processed by the filters.

HEPA Filters for Cleanrooms

HEPA filters are one of the most commonly used types of cleanroom filters. They can filter out 99.99% of all particles that are 0.3 µm or bigger, which enables them to capture and collect many of the contaminants from the air going into a cleanroom.

What Role Do HEPA and ULPA Filters Play in Cleanroom Settings?

In cleanrooms, an HVAC system first heats or cools and humidifies or dehumidifies the incoming air as needed. It then passes the air through a series of terminal HEPA or ULPA filters, which remove any microscopic particles that it might be carrying. This comprehensive process ensures the air is appropriate for the operations performed within the cleanroom, including temperature, moisture, and contaminant levels.

How Do HEPA Filters Work?

HEPA filters capture and collect airborne particulates through the use of a complex fiber web. The web traps contaminants by sieving, interception, diffusion, or inertial impaction, depending on the particulate’s size. Small-sized particles dissipate as they travel through the web until they collide with and become trapped by a fiber. Medium-sized particles are trapped through interception. Large-sized particles are trapped through inertial impaction and sieving.

Configuration of Cleanroom Filters

The filter product configurations used to depend on the requirements and restrictions of the particular application. They can include filter panels, compact filters, and deep-pleat filters. These products are processed using a variety of techniques, such as knife pleating, deep pleating using aluminum separators, and rotary mini-pleating. H&V has significant experience working with all major manufacturers of pleating equipment and can advise customers on best practices for any given application.

Types of Cleanroom HEPA Filters

Cleanroom HEPA filters come in many designs and configurations to suit different filtration applications. The most common include:

  • Fan-powered HEPA filters. These filters are highly flexible and easy to install. Standard ones offer variable speed control and feature power indicator lights.
  • Terminal diffusers. These filters are designed to be hung from tee-bar ceilings to encourage unidirectional airflow.
  • Low-profiled HEPA filters. These filters are ideal for applications where a standard-sized filter would be difficult or impossible to install.

HEPA Filters for Cleanrooms by H&V

At H&V, all of our high-efficiency cleanroom filters are constructed with low boron content and engineered for superior performance (high strength, low pressure drop). Our product selection includes:

  • Standard glass media: suitable for mini-pleat, deep-pleat, and compact filter processing
  • Perform glass media: offers superior processing characteristics and a 10% to 16% lower pressure drop compared to competitive media with the same efficiency
  • Molecular filtration media (MFM): addresses airborne molecular contamination, which can threaten process yields in many cleanroom applications

We’ve also created laminated structures that combine different technologies to enhance specific performance characteristics. To learn more about our filtration media products and how they can benefit your cleanroom application, contact us today.

  • Applications

    Applications of Cleanroom Filtration Systems

    Cleanroom filtration systems are necessary for a wide range of product and process applications, including, but not limited to, in the following areas:

    • Airborne infection isolation areas
    • Pharmaceutical production and/or packaging
    • Pharmaceutical compounding
    • GMP facilities for biopharmaceutical production
    • Medical device manufacturing
    • Laboratories
    • Semiconductor production
    • Electronics production
    • Nuclear
    • Cannabis cultivation
    • E-liquid / e-cigarette manufacturing
  • Resources

    For more information, please click on the links below for brochures, white papers, case studies and frequently asked questions:

    HEPA/ULPA Media

    Molecular Filter Media

    Molecular Filter Media Video

    Frequently Asked Questions

  • Technical Data

    To request a Technical Data Sheet please click Contact Us above and complete the form.

    Mini-Pleat
    Panel
    Mini-Pleat
    Compact
    Deep Pleat
    Alu Separator
    Standard Glass Media US
    Standard Glass Media APAC
    Standard Glass Media EMEA
    PerForm Media APAC
    PerForm Media EMEA
    High Strength Glass Media EMEA

    Standard Glass Grades US

    Grade
    Application
    Typical Filter Class
    Basis Weight
    (g/m2)
    Air Resistance @ 5.33 cm/s
    (Pa)
    Penetration 0.3µ @ 5.33 cm/s
    (%)
    Penetration 0.18µ @ 2.5 cm/s
    (%)
    HA9653 ULPA 7 9s ULPA 78 677 0.000004
    HA9643 ULPA 6 9s 5 ULPA 78 550 0.00002
    HA9633 ULPA 6 9s ULPA 78 519 0.00004
    HA9623 ULPA 5 9s 5 ULPA 78 451 0.0002
    HA9913 ULPA 5 9s ULPA 78 402 0.0004
    HA8903 ULPA 4 9s 5 ULPA 78 368 0.002 0.001
    HYB5619 HEPA 99.99% HEPA 68 353 0.002 0.003
    HB7613 HEPA 99.99% HEPA 78 343 0.004
    HYB5629 HEPA 99.98% HEPA 68 314 0.006
    HB7623 HEPA 99.98% HEPA 78 314 0.010
    HYB5939 HEPA 99.97% HEPA 68 274 0.015
    HB7633 HEPA 99.97% HEPA 78 289 0.015
    HC4683 Sub-HEPA Sub-HEPA 78 260 0.045
    HD2063 95% DOP 95% DOP 78 157 3
    HD2583 95% DOP 95% DOP 78 113 5.5

    Standard Glass Media APAC

    Grade
    Application
    Typical Filter Class
    Basis Weight
    (g/m2)
    Air Resistance @ 5.33 cm/s
    (Pa)
    Penetration 0.3µ @ 5.33 cm/s
    (%)
    HA9653 Ulpa 7 9s ULPA 78 677 0.000004*
    HA9633 Ulpa 6 9s ULPA 78 519 0.00004*
    HA9623 Ulpa 5 9s 5 ULPA 78 451 0.0002*
    HA9613 Ulpa 5 9s ULPA 78 412 0.0004*
    HA8603 Ulpa 5 9s ULPA 78 373 0.0020
    HB7613 Hepa 99.99% HEPA 78 343 0.004
    HB7623 Hepa 99.98% HEPA 78 314 0.010
    HB7633 Hepa 99.97% HEPA 78 289 0.015
    HC4683 Sub-Hepa Sub-HEPA 78 260 0.045
    HD2583 Sub Hepa Glass 78 113 5.5
    HD2063 Hepa 99.99% HEPA 78 157 3.0

    Standard Glass Media EMEA

    Grade
    Typical Filter Class EN1822
    Filter Class @ Media Velocity
    Basis Weight
    (g/m2)
    Media Velocity
    (cm/s)
    Air Resistance @ 5.33 cm/s
    (Pa)
    MPPS Penetration @ Media Velocity
    (%)
    HA8303 U16 H14 78 2.50 495 0.00015
    HA8323 U15 H14 78 2.50 435 0.00045
    HB5773 H14 H14 78 2.50 405 0.0006
    HB5613 H13/H14 H13 78 2.50 365 0.0025
    HB5451* H13 H13 90 2.50 352 0.005
    HB5763 H13 H13 78 2.50 330 0.008
    HB5703 H13 E12 78 5.33 305 0.056
    HC4313 E12/H13 E12 76 5.33 285 0.15
    HC3313 E11/E12 E11 75 5.33 245 0.4
    HD2293 E10/E11 E10 78 5.33 160 3.8

    * Meets the requirements of the Code on Nuclear Air and Gas Treatment, AG-1-2017, FC-I-3000 & FC-I-4000, 09 February 2018

    PerForm Media APAC

    Grade
    Typical Filter Class EN1822
    Filter Class @ Media Velocity
    Basis Weight
    (g/m2)
    Media Velocity
    (cm/s)
    Air Resistance @ 5.33 cm/s
    (Pa)
    MPPS Penetration @ Media Velocity
    (%)
    HB5893 U15 H14 70 2.50 360 0.0005
    HB5593 H14 H13 70 2.50 310 0.004
    HB5494 H13 H13 70 2.50 295 0.0075
    HB5793 H13 E12 70 5.33 265 0.07
    HA8393 E11 E11 70 5.33 210 0.36

    PerForm Media EMEA

    Grade
    Typical Filter Class EN1822
    Filter Class @ Media Velocity
    Basis Weight
    (g/m2)
    Media Velocity
    (cm/s)
    Air Resistance @ 5.33 cm/s
    (Pa)
    MPPS Penetration @ Media Velocity
    (%)
    HB5893 U15 H14 70 2.50 360 0.0005
    HB5593 H14 H13 70 2.50 310 0.004
    HB5494 H13 H13 70 2.50 295 0.0075
    HB5793 H13 E12 70 5.33 265 0.07
    HC3393 E11 E11 70 5.33 210 0.36
    HD2393 E10 E10 70 5.33 132 3.7

    High Strength Glass Media EMEA

    Grade
    Typical Filter Class EN1822
    Filter Class @ Media Velocity
    Basis Weight
    (g/m2)
    Media Velocity
    (cm/s)
    Air Resistance @ 5.33 cm/s
    (Pa)
    MPPS Penetration @ Media Velocity
    (%)
    DOP Penetration 0.3µ @ 5.3cm/s
    (%)
    HB13792 U15 H14 81 2.50 400 0.00036
    HB12792 H13 H13 81 2.50 320 0.006
    HB15826 E12 E12 81 5.33 280 0.059
    HD 2433 E11 E11 78 5.33 154 3
    HE 1613 E10 E10 81 5.33 135 5

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